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Electrolyte analyzers measure electrolyte levels in the human body to detect metabolic imbalances and measure renal and cardiac function. The electrolytes measured include sodium (Na+), potassium (K+), chloride (Cl-) and bicarbonate (HCO3- or CO2). Electrolyte analyzers are used in hospital and reference laboratories, and also point of care settings. Most electrolyte analyzers use blood plasma, serum, or urine samples; some analyzers can use whole blood (for faster turn around time) and cerebrospinal fluid (CSF). Electrolytes are measured using ion selective electrodes (ISE) and colorimetric and photometric techniques.